NRC — Zebrafish research facility
Last Update: April 2, 2025
Halifax, NS
Zebrafish research facility in Halifax
NRC — Zebrafish research facility at a glance
Eligible Funding
- No Condition
Timeline
- Open Date : November 14, 2019
Financing Type
Researchers And Facilities
Expert Advice
Eligible Industries
- Professional, scientific and technical services
- Health care and social assistance
Grant Providers
- National Research Council Canada (NRC)
- Government of Canada
Status
Open
Overview of the NRC — Zebrafish research facility program
Fee-for-service facility offering testing services for the evaluation of toxicological and pharmacological activity in the areas of natural health products and human health therapeutics.
Eligible projects & activities
This grant supports research and development initiatives using the zebrafish model to advance in vivo testing methods and disease model validation. The eligible projects focus on toxicity and pharmacological activity evaluation, leveraging genetic conservation with human genomes.
- Development and validation of in vivo assays for industry-specific applications.
- Characterization of bioactivity and toxicity using zebrafish models.
- Evaluation of toxicological and pharmacological activity for natural health products and human therapeutics.
- Creation of customized disease models through transgenesis and genome modification.
Examples of admissible projects:
$ 250,000
Identification of mechanisms of action for new natural health products using zebrafish models
$ 150,000
Development of high-throughput behavioral tracking protocols for zebrafish studies
$ 180,000
Pilot study on the effectiveness of intracerebroventricular administration in zebrafish models
$ 200,000
Establishment of a zebrafish preclinical research lab, including equipment for toxicity profiling
$ 220,000
Pharmacological testing of human health therapeutics using intravenous administration
$ 300,000
Implementation of omics techniques in zebrafish for natural product drug discovery
Eligibility criteria of the NRC — Zebrafish research facility program
Who is eligible?
Companies in the biotechnology, pharmaceutical, natural health product, and human health therapeutics industries can apply for this grant to utilize the zebrafish research facility for developing and validating a range of in vivo assays, methods, and disease models for industry-specific applications.
Eligible expenses
This facility encourages projects that leverage the zebrafish model for innovative and cost-effective research and testing. Eligible projects include developing and validating assays that assist in pharmacological and toxicological research, especially in the field of human health therapeutics.
- Development and validation of in vivo assays using zebrafish for pharmacological and toxicological research.
- Collaborative research projects focusing on natural health products and human health therapeutics using zebrafish models.
- Evaluation of toxicological and pharmacological activity of extracts, complex mixtures, and purified compounds.
Eligibility criteria of the NRC — Zebrafish research facility program
There are evaluation and selection criteria for this grant. The evaluation and selection criteria include:
- Scientific merit and significance of the proposed research
- Alignment with industry-specific applications
- Feasibility and appropriateness of the experimental approach
- Potential impact on toxicological and pharmacological studies
- Potential for collaboration and knowledge exchange
How to apply to the NRC — Zebrafish research facility program
1
Preparing the application
- Review the eligibility criteria for the grant
- Prepare the required documents for the application
2
Filling out the documents
- Fill out the grant application form
- Attach the necessary supporting documents
3
Submitting the application
- Submit the complete application within the given deadlines
- Wait for the decision from the grants award committee
Additional information
The grant applicant should be aware of some facility-specific advantages and contact points that may assist in the application process:
- The zebrafish research facility offers significant cost advantages due to its ability to conduct research at just 0.1 to 1.0 percent of the cost of traditional rodent models.
- Testing at the facility requires only small quantities of test compounds, which aids in the early identification of lead drug candidates and potential issues.
- The facility has the expertise to offer customized disease models through techniques like transgenesis and genome modification.
- The facility includes advanced capabilities like omics techniques, preclinical toxicity profiling, and high-throughput behavioural tracking, among others.
- Potential applicants can contact business and technical inquiry points directly for more information: James De Pater for business inquiries and Lee Ellis for technical inquiries.
Apply to this program
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