NRC — Cell Culture Pilot Plant
Montréal, QC, Canada
Biologics and vaccine production facility in Montreal
grant_single_labels|summary
grant_single|eligibleFinancing
- grant_single|noCondition
grant_single|deadlines
- grant_single|openingDateNovember 14, 2019
grant_single|financingType
Researchers And Facilities
grant_single|eligibleIndustries
- Manufacturing
- Professional, scientific and technical services
- Health care and social assistance
grant_single|grantors
- Government of Canada
- National Research Council Canada (NRC)
grant_single|status
grant_card_status|open
grant_single_labels|preview
Fee-for-service cell culture pilot plant offering development and scale-up for the production of biologics and vaccines using CHO, HEK 293 and other animal cell expression systems.
grant_single_labels|projects
There are eligible projects and activities for this grant. The activities include:
- Development and scale-up of batch, fed-batch or perfusion cell culture processes up to 500 L scale for biologics production
- Scale-up of viral production and purification processes
- Scale-up of transient transfection processes
- Development of cell culture media and feeding strategies for process optimization
- In-process assay development
- Customized, hands-on training on bioreactor operation up to 500 L scale
grant_single|admissibleProjectsExample
$220,000
Calgary
Development of custom cell culture media for the optimization of an antibody production process
$200,000
Edmonton
Conducting hands-on training for bioreactor operation up to 500 L scale
$250,000
Toronto
Developing a 500 L scale bioreactor process for vaccine production using CHO cells
$270,000
Halifax
Development and scale-up of a perfusion cell culture process for biologics production
$280,000
Winnipeg
Optimization of transient transfection processes for the production of therapeutic proteins
$300,000
Vancouver
Scale-up of viral production processes for gene therapy applications
grant_single_labels|admissibility
Eligibility criteria:
- Canadian biotechnology companies
- Businesses involved in pilot-scale production and purification of biologics, viral vectors, and vaccines
grant_eligibility_criteria|eligible_expenses
Yes, eligible expenses for this grant include:
- Development and scale-up of batch, fed-batch or perfusion cell culture processes up to 500 L scale for biologics production
- Scale-up of viral production and purification processes
- Scale-up of transient transfection processes
- Development of cell culture media and feeding strategies for process optimization
- In-process assay development
- Customized, hands-on training on bioreactor operation up to 500 L scale
grant_single_labels|criteria
Grant applications will be assessed based on key criteria including scientific excellence, feasibility, impact, and alignment with the objectives of the Human Health Therapeutics Research Centre.
- Scientific excellence
- Feasibility of the proposed project
- Potential impact of the project
- Alignment with the objectives of the Human Health Therapeutics Research Centre
grant_single_labels|register
- Step 1: Review the grant application guidelines to understand eligibility criteria and submission requirements.
- Step 2: Gather all necessary documents and information, such as project details, budget, and supporting materials.
- Step 3: Complete the application form following the instructions provided by the grant agency.
- Step 4: Submit the grant application by the specified deadline, ensuring all components are included and accurate.
- Step 5: Await the review process, which may involve evaluation by reviewers and potential interviews or clarifications.
- Step 6: If successful, follow any additional instructions from the grant agency regarding funding disbursement and reporting requirements.
Apply to this program
Grant Summary
The NRC’s Human Health Therapeutics Research Centre offers advanced bioprocessing services and equipment for the production of biologics and vaccines. Their cell culture pilot plant provides process development and scale-up capabilities for various expression systems, including CHO and HEK293.
Grant Details
The National Research Council of Canada's (NRC) Human Health Therapeutics Research Centre provides cutting-edge bioprocessing services to support the development and production of biologics and vaccines. With a team of experts in cell biology, purification, and engineering, the Centre offers services such as process optimization, scale-up, and medium development to enhance product yield.
The Centre's cell culture pilot plant features state-of-the-art equipment, including bioreactors of up to 500 L capacity, centrifugation systems, filtration units, and chromatography columns for product purification. Their facilities are ideal for pilot-scale production and purification of recombinant proteins, viral vectors, and vaccines, enabling companies to optimize and scale-up their bioprocesses.
Collaborating with the NRC's team allows companies to access specialized expertise in cell culture, medium development, and process optimization, ultimately leading to the production of high-quality biologics and vaccines. The Centre's commitment to fostering the Canadian biomanufacturing sector ensures a strong and prosperous future for biotechnology in Canada.
If you are looking to develop new bioprocessing techniques or optimize existing ones, the NRC's Human Health Therapeutics Research Centre is your go-to partner. Their comprehensive services, advanced equipment, and experienced team make them a valuable resource for companies engaged in biologics and vaccine production.