Rôle de la Fondation Isaac dans l'écosystème du financement de la recherche
La Fondation Isaac se distingue comme un bailleur de fonds charitablededicated to accelerating the development of treatments for rare genetic diseases known as mucopolysaccharidoses (MPS). Since 2007, the organization has committed over $2 million to research grants supporting innovative projects around the world.
Domaines de financement
The foundation funds various research approaches including gene therapy, stem cell therapy, enzyme replacement therapy, and pharmacological interventions. Their funded projects span from basic science research to clinical trials.
Projets de recherche financés notables
- Kommodo Therapeutics - Engineering Memory T Cells for Long-Term Enzyme Replacement Therapy
- Dr. Brian Bigger - Brain-targeted stem cell gene therapy for MPS II (clinical trial started 2023)
- Dr. Alberto Auricchio - Gene therapy for MPS VI (phases I and II completed)
- Dr. Calogera Simonaro - Novel therapy Pentosan Polysulfate currently in clinical trial
- Dr. Roberto Giugliani - Clinical trial evaluating Losartan for aortic root dilation in MPS patients
Impact et transparence
La fondation est fière d'affirmer que 99% des dons sont directement reversés aux activités caritatives. En tant qu'organisme de bienfisance enregistré, elle délivre des reçus aux fins d'impôts pour tous les dons reçus.
