
NRC — Microbial fermentation pilot plant facility research facility
At a glance
- No Condition
- Unspecified
- All industries
Overview
Fee-for-service access to broad range of equipment to rapidly convert laboratory results into industrial processes up to the 1,500-litre scale to assist with implementing current Good Manufacturing Practices (cGMP).
Activities funded
This grant is designed to support research and development initiatives within the biotechnology sector, particularly focused on microbial fermentation processes. Eligible projects or activities facilitate the scale-up and optimization of bioprocesses using specialized facilities and expertise.
- Engineering and selection of recombinant strains including Escherichia coli, Methylo-bacterium extorquens, and yeast (Pichia; Saccharomyces).
- Production of biotechnology products such as peptides, proteins, nutraceuticals, organic acids, polymers, and probiotics.
- Screening and optimization of media, microorganisms, cell lines, and cultivation conditions.
- Bioprocess optimization and scale-up to 1500 L.
- Handling and bioprocessing of methanol-oxidizing microorganisms.
- Testing of new monitoring/control equipment and reagents used in bioprocessing.
- Purification and analytical services supporting bioprocessing operations.
- Technical and scientific guidance tailored to bioprocess development.
- Provision of general or specialized training in microbial fermentation and bioprocessing.
- Preparation and documentation tailored to specific bioprocessing needs.
Eligibility
Eligibility for this facility's services and resources is specifically tailored to small and medium enterprises (SMEs) with certain requirements.
- The applicant should be a small and medium enterprise (SME) with limited capacity to invest in pilot-scale facilities compatible with current Good Manufacturing Processes (cGMP).
- The company should be engaged in the biotechnology sector, requiring services like genome engineering, strain selection, or microbial fermentation process development.
- The need for scaling up laboratory results to industrial processes up to the 1500 L scale should be demonstrated.
Who is eligible?
Small and medium enterprises (SMEs)
Selection criteria
Evaluation and selection criteria for this grant include: - Expertise in microbial fermentation and bioprocessing - Relevance of the project to industrial applications - Importance of the research to the biotechnology industry - Feasibility and scalability of the proposed work - Potential for commercialization and impact on the industry - Alignment with current good manufacturing practices (cGMP) if applicable - Track record of the research team and their ability to deliver results - Innovation and novelty of the proposed approach - Budget and resource management - Compatibility with the goals and objectives of the funding organization
How to apply
Preliminary contact
- Contact Mélanie Arbour or Luke Masson to discuss the needs and possibilities for collaboration.
- Assess the alignment between your project's needs and the capabilities of the pilot plant.
Definition of the project
- Work with the NRC team to define the project objectives and the scope of the work.
- Identify the resources and services needed for the project.
Submission of the request
- Prepare a document describing the project, the objectives, and the specific needs.
- Include any necessary documentation to support your request, such as technical details and timelines.
- Send your request via email to Mélanie Arbour or Luke Masson, ensuring all interested parties are included.
Confirmation of receipt and validation
- Receive a confirmation of receipt of your request from the CNRC team.
- Participate in additional discussions to adjust and validate your project in collaboration with the CNRC team.
Additional information
Here are additional relevant details for this grant:
- The facility offers specialized training tailored to the needs of SMEs and other clients.
- Cutting-edge equipment is available for testing new monitoring and control equipment or reagents.
- The NRC provides multidisciplinary expertise with a team of microbiologists, engineers, chemists, and biochemists.
- The facility has a strong track record, with over 25 years of experience in supporting the biotech and research community.
- SMEs are particularly encouraged to collaborate, as the facility offers unique resources that may not be otherwise accessible to them.
Contacts
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